Germ Cells are Forever

Germ cells transmit the potential to build a completely new organism to their offspring. The mechanisms that endow germ cells with the ability to propagate totipotency across generations are poorly understood. The Lehmann lab studies how germ cells are set apart from somatic cells during embryogenesis, how early germ cells are guided to the gonad and how germ cell fate is maintained and protected throughout life in order to generate egg and sperm.